Abstract
We report the first case of a clinically significant delayed hemolytic transfusion reaction associated with anti-Aua antibody in an 18-year-old male with beta-thalassemia and pre-existing anti-D, -C, and -Jkb antibodies. Following transfusion with antigen-negative red blood cells, a new anti-Aua antibody was identified, confirmed by a positive Monocyte Monolayer Assay. These findings underscore the importance of vigilance in identifying rare antibodies that may impact transfusion strategies and advanced therapeutic options.
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Authors
Aleksander Luniewski Department of Pathology, University of Virginia, Charlottesville, VA, United States of America
Courtney E. Lawrence American Red Cross, Biomedical Services, Richmond, VA, United States of America
C. John Luckey Department of Pathology, University of Virginia, Charlottesville, VA, United States of America
James D. Gorham
Department of Pathology, University of Virginia, Charlottesville, VA, United States of America
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