Abstract
Introduction
Autoimmune haemolytic anaemia (AIHA) is a rare condition in children caused by the presence of auto-antibodies directed against red blood cell surface antigens, leading to premature red cell destruction1,2. It is classified as warm, cold, including cold haemagglutinin disease and paroxysmal cold haemoglobinuria, or mixed, according to the thermal range of the auto-antibody. AIHA can be idiopathic or secondary. The overall annual incidence is reported to be 1-3 cases/100,000 people and approximately 0.2 cases/1,000,000 individuals less than 20 years of age. […]
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Saverio Ladogana Paediatric Onco-haematology Unit "Casa Sollievo della Sofferenza" Hospital, IRCCS, San Giovanni Rotondo
Matteo Maruzzi Paediatric Onco-haematology Unit "Casa Sollievo della Sofferenza" Hospital, IRCCS, San Giovanni Rotondo
Piera Samperi Paediatric Onco-haematology Unit, Azienda "Policlinico Vittorio Emanuele", Department of Clinical and Experimental Medicine, University of Catania, Catania
Annalisa Condorelli Paediatric Onco-haematology Unit, Azienda "Policlinico Vittorio Emanuele", Department of Clinical and Experimental Medicine, University of Catania, Catania
Maddalena Casale Department of Women, Children and General and Specialised Surgery, "Luigi Vanvitelli", University of Campania, Naples
Paola Giordano Department of Paediatrics "B. Trambusti", Policlinico Hospital "Giovanni XXIII", Bari
Lucia D. Notarangelo Paediatric Onco-haematology Unit, Children's Hospital "Spedali Civili", Brescia
Piero Farruggia Paediatric Onco-haematology Unit, "Civico" Hospital, Palermo
Fiorina Giona Haematology, Department of Cellular Biotechnologies and Haematology, "Sapienza" University, Rome
Agostino Nocerino Department of Paediatrics, "S. Maria della Misericordia" University Hospital, University of Udine, Udine
Silvia Fasoli Paediatric Unit, "Carlo Poma" Hospital, Mantua
Maria L. Casciana Paediatric Unit, "Carlo Poma" Hospital, Mantua
Maurizio Miano Clinical and Experimental Haematology Unit, "G. Gaslini" Children's Hospital, Genoa
Fabio Tucci Paediatric Haematology-Oncology Unit, Meyer Paediatric Hospital, Florence
Tommaso Casini Paediatric Haematology-Oncology Unit, Meyer Paediatric Hospital, Florence
Paola Saracco Paediatric and Adolescent Science Department, University of Turin. Turin
Wilma Barcellini Onco-haematology, Physiopathology of Anaemia Unit, IRCCS "Ca' Granda Foundation", Ospedale Maggiore Policlinico, Milan, Italy
Silverio Perrotta Department of Women, Children and General and Specialised Surgery, "Luigi Vanvitelli", University of Campania, Naples
Giovanna Russo Paediatric Onco-haematology Unit, Azienda "Policlinico Vittorio Emanuele", Department of Clinical and Experimental Medicine, University of Catania, Catania
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