Abstract

We report the case of a woman with trisomy 9 who showed atypical, mixed-field agglutination of ABO blood type. Her red blood cells showed strong agglutination with anti-A monoclonal antiserum and atypical mixed-field agglutination with anti-B monoclonal antiserum. The results of the genotyping of her father and mother revealed A101/B101 and O01/O02, respectively; however, only B101/O01 was detected in the patient because of the characteristics of the test method used. Multiplex analysis would help in understanding the pathophysiology of abnormal findings; nevertheless, careful data interpretation is required.

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Authors

Sena Fujii Department of Blood Transfusion, Kyoto Prefectural University of Medicine, Kyoto, Japan

Yuji Shimura Department of Blood Transfusion, Kyoto Prefectural University of Medicine, Kyoto, Japan

Keiichi Shigehara Department of Pediatrics, Ayabe City Hospital, Kyoto, Japan

Yuji Sasada Department of Blood Transfusion, Kyoto Prefectural University of Medicine, Kyoto, Japan

Tohru Inaba Department of Infection Control & Laboratory Medicine, Kyoto, Japan

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